A BIST solution for frequency domain characterization of analog circuits

This work presents an efficient implementation of a BIST solution for frequency characterization of analog systems. It allows a complete characterization in terms of magnitude and phase, including also harmonic distortion and offset measurements. Signal generation is performed using a modified filter, while response evaluation is based on 1storder ÓÄ modulation and very simple digital processing. The signal generator and the response analyzer have been implemented using the Switched-Capacitor (SC) technique in a standard 0.35ìm-3.3V CMOS technology. Both circuits have been separately validated, and an on-board prototype of the complete test system for frequency characterization has been implemented. Experimental results verify the functionality of the proposed approach, and a dynamic range of [email protected] (1MHz clock) has been demonstrated.Gobierno de España TEC2007-68072/MIC, TSI 020400- 2008-71Catrene European Project 2A105SR

1.2V, 1.96mW @ 2.4GHz CMOS-90nm switched-transconductor mixer

This paper presents the design of a fully differential double balanced switched transconductor mixer for ZigBee applications in the 2.4GHz band. It provides programmable conversion gain by using an active load stage. The design includes RF and LO input matching networks. It has been implemented in a 90nm 1P9M CMOS process. Post-layout simulations show conversion gains of 12dB/20dB, NF of 18.9dB/18.1dB and power consumption of 4.1mW/4.4mW at high and low gain mode respectively from a 1.2V power supply. It also offers very good linearity performance.España, Gobierno TEC2007- 68072 / MICEspaña, Junta de Andalucía ACATEX (P09-TIC-5386

Analog sinewave signal generators for mixed-signal built-in test applications

This work presents a technique for the generation of analog sinusoidal signals with high spectral quality and reduced circuitry resources. Two integrated demonstrators are presented to show the feasibility of the approach. The proposed generation technique is based on a modified analog filter that provides a sinusoidal output as the response to a DC input. It has the attributes of digital programming and control, low area overhead, and low design effort, which make this approach very suitable as test stimulus generator for built-in test applications. The demonstrators—a continuous-time generator and a discrete-time one—have been integrated in a standard 0.35 μm CMOS technology. Simulation results and experimental measurements in the lab are provided, and the obtained performance is compared to current state-of-the-art on-chip generation strategies.Gobierno de España TEC2007-68072/MIC, TSI-020400-2008-71/MEDEA+2A105, CATRENE CT302Junta de Andalucía P09-TIC-538

Testing mixed-signal cores: a practical oscillation-based test in an analog macrocell

A formal set of design decisions can aid in using oscillation-based test (OBT) for analog subsystems in SoCs. The goal is to offer designers testing options that do not have significant area overhead, performance degradation, or test time. This work shows that OBT is a potential candidate for IP providers to use in combination with functional test techniques. We have shown how to modify the basic concept of OBT to come up with a practical method. Using our approach, designers can use OBT to pave the way for future developments in SoC testing, and it is simple to extend this idea to BIST.European Union 2635

On-chip evaluation of oscillation-based-test output signals for switched-capacitor circuits

This work presents a simple and low-cost method for on-chip evaluation of test signals coming from the application of the Oscillation-Based-Test (OBT) technique. This method extracts the main test signal features (amplitude, frequency and DC level) in the digital domain requiring just a very simple and robust circuitry. Experimental results obtained from an integrated chip demonstrate the feasibility of the approac

Energy-Aware Low-Power CMOS LNA with Process-Variations Management

A reconfigurable low-noise amplifier (LNA) with digitally controllable gain and power consumption is presented.This architecture allows increasing power consumption only when required, that is, to improve LNA’s radiofrequency performance at extreme communication-channel conditions and/or to counteract the effect of process, voltage, and temperature variations.The proposed design leads to significant power saving when a relaxed operation is acceptable. The LNA is implemented in a 130nm 1.2V CMOS technology for a 2.4GHz IEEE-802.15.4 application. Simulated LNAperformance (taking into account theworst cases under process variations) is comparable to recently published worksCAPES-Brazil 176/12Ministerio de Asuntos Exteriores y Cooperación D/024124/09Junta de Andalucía P09-TIC- 5386Ministerio de Economía y Competitividad TEC2011-2830

A 2.5MHz bandpass active complex filter With 2.4MHz bandwidth for wireless communications

This paper presents a fully differential 8thorder transconductor-based active complex filter with 2.4MHz bandwidth and centered at 2.5MHz, designed in a 90nm 2.5V 7M and MIM capacitors CMOS process technology. The filter compliants with the requirements of the IEEE802.15.4 standard. Simulation results including mismatching and process variations over the extracted view of the circuit are shown. The filter has a nominal gain of 12dB, good selectivity (20dB@2MHz offset), high image rejection (51dB nominal) and low power consumption (3.6mA @2.5V).Junta de Andalucía TIC-927Gobierno de España TEC2007-6807

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Post-Franco Theatre

In the multiple realms and layers that comprise the contemporary Spanish theatrical landscape, “crisis” would seem to be the word that most often lingers in the air, as though it were a common mantra, ready to roll off the tongue of so many theatre professionals with such enormous ease, and even enthusiasm, that one is prompted to wonder whether it might indeed be a miracle that the contemporary technological revolution – coupled with perpetual quandaries concerning public and private funding for the arts – had not by now brought an end to the evolution of the oldest of live arts, or, at the very least, an end to drama as we know it

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection